COVID-19 vaccine uptake and effectiveness in adults aged 50 years and older in Wales UK: a 1.2m population data-linkage cohort approach영국 웨일즈에서 50세 이상 성인의 COVID-19 백신 섭취 및 효과: 120만 인구 데이터 연결 코호트 접근법Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] 95%CI Adult affected Alpha approach BNT162b2 ChAdOx1 ChAdOx1 vaccine ChAdOx1 vaccines Characteristics Cohort collected data Coverage COVID-19 COVID-19 vaccine COVID-19 vaccines death Delta dose doses Effectiveness estimate first dose followed by Hospital admission immunization Infection linkage of BNT162b2 Older outcome outcomes PCR positive PCR positive SARS-CoV-2 infection post vaccination predominant SARS-CoV-2 SARS-COV-2 infection schedule second dose Seven strain vaccination vaccination. Vaccine variants Wales [DOI] 10.1080/21645515.2022.2031774 PMC 바로가기 [Article Type] Article
Reverse transcriptase-free detection of viral RNA using Hemo Klentaq DNA polymeraseArticle Published on 2022-12-152022-11-15 Journal: Analytical biochemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] affected amplification Analysis can be used caused comparable COVID-19 Degraded RNA demonstrated determine DNA polymerase Efficiency freeze-thaw cycles limitations Nasopharyngeal swab Nearby Nearby primers overcome pandemic patients PCR polymerase chain polymerase chain reaction Primers provide provided reliability reverse transcriptase Reverse transcriptase activity reverse transcription RNA RT-PCR SARS-CoV-2 SARS-CoV-2 detection target transcriptase Viral RNA Viral RNA. [DOI] 10.1016/j.ab.2022.114960 PMC 바로가기
A novel statistical method predicts mutability of the genomic segments of the SARS-CoV-2 virusResearch Article Published on 2022-12-132022-10-29 Journal: Qrb Discovery [Category] COVID-19, [키워드] affected antiviral drugs approach candidate coding regions codon conserved correlated correlation determine develop disease distribution effective epitope Frequency genomic identify immunogenic peptide large-scale analysis mutability offer overcome pandemic pathogenesis of SARS-CoV-2 predict predicted Protein SARS-CoV-2 SARS-CoV-2 virus SARS-CoV2 scientist sequence Seven spike glycoprotein statistical statistical analysis target the SARS-CoV-2 virus treatments for COVID-19 Vaccine viral genome viral mutation whole genome whole genome sequence Word Ranking [DOI] 10.1017/qrd.2021.13 PMC 바로가기 [Article Type] Research Article
Signs and symptoms of COVID-19 in patients with multiple sclerosisArticle Published on 2022-12-012022-11-16 Journal: European journal of neurology [Category] COVID19(2023년), SARS, 변종, [키워드] affected Ageusia alcohol Analysis Anosmia anti-CD20 therapy association chest pain clinical collected Comorbidity coronavirus disease COVID-19 COVID-19 symptom COVID-19 symptoms Delta Demyelinating diseases difference disease-modifying treatment Factor flu-like symptom Frequency greater identify Infection investigated joint less Linear regression model multiple sclerosis Neurological disorders neurological disorders. number of symptom Occurrence Odds ratio Older outcome Pain Patient Rash recognize risk factor Shortness of breath SIGN similarity smoke smoker Symptom symptoms of COVID-19 Tachycardia therapeutic approach therapy variant [DOI] 10.1111/ene.15554 PMC 바로가기
Molecular and pro-inflammatory aspects of COVID-19: The impact on cardiometabolic healthArticle Published on 2022-12-012022-11-15 Journal: Biochimica et biophysica acta. Molecular basis of [Category] COVID19(2023년), SARS, 진단, [키워드] affected cardiometabolic cardiovascular Cluster Complication country COVID COVID-19 COVID-19 pandemic COVID-19 severity CVD cytokine cytokine production diabetes Final hallmark Health hypertension IL-6 IL10 IL2 IL4 IL8 immune system increased the risk infected patient Inflammation inflammatory state influence molecular molecular. morbidity and mortality obese pathophysiological Patient predictor pro-inflammatory reported resulting SARS-CoV2 systemic damage target type 2 diabete virus [DOI] 10.1016/j.bbadis.2022.166559 PMC 바로가기
COVID-19 breakthrough infections and humoral immune response among BNT162b2 vaccinated healthcare workers in Malaysia말레이시아에서 BNT162b2 백신을 접종한 의료 종사자의 COVID-19 획기적인 감염 및 체액성 면역 반응Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] 95% CI affected age Anti-S1 Anti-spike antibody Antibody Response antibody titres association Asymptomatic Asymptomatic individuals blood sample Blood samples BNT162b2 booster vaccination breakthrough Breakthrough infection breakthrough infections collected COVID-19 COVID-19 infection delta variant detectable domain geometric mean geometric mean titre GMT HCWs healthcare healthcare worker Healthcare workers humoral humoral immune response Humoral immunity IgG IgG assay individual individuals Infection investigated Malaysia not different notable outcome Participants prospective cohort study Protein response significantly significantly higher Support symptomatic the antibody response vaccination Vaccine vaccine doses vaccine. waned was measured [DOI] 10.1080/22221751.2022.2065936 PMC 바로가기 [Article Type] Article
Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-2Article Published on 2022-12-012022-11-16 Journal: Virulence [Category] COVID19(2023년), SARS, 변종, [키워드] affected Analysis ancestor Asymptomatic asymptomatic patients clinical outcomes correlation Degradation deletion of the untranslated region demonstrated Deterioration driving early stage evaluate Evolution explain genetic influence Genome hospitalized patient indicated mathematical Mortality mortality rate Mutation nucleic acid nucleic acid degradation system Patient SARS-CoV-2 SARS-COV-2 infection significantly significantly more similarity strain Support Symptoms the epidemic Toxicity UTR viral genome viral toxicity viral toxicity. virulence virus virus genome was performed [DOI] 10.1080/21505594.2022.2132059 PMC 바로가기
A Qualitative Study of COVID-19 Vaccine Decision Making Among Urban Native AmericansResearch article Published on 2022-12-012022-10-05 Journal: Vaccine: X [Category] 유전자 메커니즘, [키워드] Affect affected agency American Community community health Community-engaged research conducted COVID-19 COVID-19 vaccination COVID-19 vaccine Decision making described develop distribution Evidence Factor finding group Health Health disparities implication IMPROVE information investigated lack majority Misconception morbidity and mortality Native Native Americans occurred organization participant public health Qualitative recommendation recruited reported resource second Significant suggested Support thematic analysis urban vaccination Vaccine Vaccine development Vaccine hesitancy widespread [DOI] 10.1016/j.jvacx.2022.100212 [Article Type] Research article
Oil and gold return spillover and stock market elasticity during COVID-19 pandemic: A comparative study between the stock markets of oil-exporting countries and oil-importing countries in the Middle EastResearch article Published on 2022-12-012022-10-05 Journal: Resources Policy [Category] 변종, [키워드] affected Bahrain country COVID-19 COVID-19 pandemic Elasticity Gold price greater heterogeneous Jordan Kuwait Last medium Middle East Oil Oil prices Partial wavelet coherence test Saudi Arabia significantly Stock market elasticity Turkey Wavelet coherence test [DOI] 10.1016/j.resourpol.2022.102935 [Article Type] Research article
The impact of COVID-19 non-pharmaceutical interventions on HIV care continuum in China: An interrupted time series analysisResearch article Published on 2022-12-012022-10-05 Journal: The Lancet Regional Health - Western Pacific [Category] 변종, [키워드] 95% CI affected Analysis Antiretroviral therapy ART Care CD4 count CD4 counts CD4+ T cell China collected continuum COVID-19 decrease diagnose diagnoses Diagnosis disease early stage effort evaluate expected finding foundation funding HIV hospital implementation increase in Infectious disease Interrupted time series analysis interval Intervention maintain majority male median time natural non-pharmaceutical interventions (NPIs) NPI NPIs occurred outcome outcomes Poisson Prophylaxis public health emergency reached Region Regression model Science study period time interval time intervals Transmission were recorded [DOI] 10.1016/j.lanwpc.2022.100569 [Article Type] Research article